This cross-over, placebo-controlled, double-blind study involved healthy subjects [males and females; mean age=32±14 years; body mass index=26.4±5.0 ranging from 19.1 to 36.8kg/m2] (Study ID Number: PBRC10043). Each subject reported to the Inpatient Unit on two occasions one week apart. After an overnight fast, subjects had an IV line placed and baseline blood samples were drawn at -30, -15, and 0 minutes. Subjects were then asked to swallow the capsules of Growth Factor-9 supplement or an identical-looking placebo. Blood was drawn at 15, 30, 60, 90 and 120 minutes for assay.
After 120 minutes, mean GH levels had increased 682% from baseline (0.17 to 1.33ng/ml) and were significantly higher than placebo (P=0.01). In addition, a significantly higher mean AUC was observed after taking the supplement [20.4 (95% CI: 19.9-21.0ng/ml) vs. 19.7 (95% CI: 18.7-20.6ng/ml); P=0.04].